Find coaches from Itajaí to Santa Maria, RS, BR

Previously seen journeys

Next departures from Itajaí to Santa Maria on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
União Santa Cruz
Terminal Rodoviário Internacional de Itajaí
Terminal Rodoviário de Santa MariaNo tags
União Santa Cruz
Itajaí Bus Terminal
Terminal Rodoviário de Santa MariaNo tags
União Santa Cruz
Itajaí Bus Terminal
Terminal Rodoviário de Santa MariaNo tags
União Santa Cruz
Itajaí Bus Terminal
Terminal Rodoviário de Santa MariaNo tags
União Santa Cruz
Itajaí Bus Terminal
Terminal Rodoviário de Santa MariaNo tags

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Bus Itajaí to Santa Maria, RS, BR: Trip Overview

Average ticket priceUS$80
Average bus trip duration13h 45m
Number of daily buses3
Earliest bus departure07:15
Distance364 miles
Latest bus departure20:00

Itajaí to Santa Maria Bus

Busbud helps you find a bus from Itajaí to Santa Maria. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Itajaí to Santa Maria will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santa Maria from Itajaí, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Itajaí - Santa Maria, RS, BR

  1. How far is Santa Maria from Itajaí by coach?

    The journey from Itajaí to Santa Maria by coach covers an approximate distance of 368 miles (593 km).

  2. Is there a way to reach Santa Maria from Itajaí without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
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12/10
US$49
Today
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15/10
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busbud logoThe cheapest trip from Itajaí to Santa Maria, RS, BR was searched and found on 12 Oct 2025 with a price of US$49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Itajaí to Santa Maria, RS, BR as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Itajaí and Santa Maria!

Much more than a mere vehicle taking you from Itajaí to Santa Maria, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Itajaí to Santa Maria.

Tune out to the fine sounds of your best music playlist on your bus trip from Itajaí to Santa Maria while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Itajaí by bus?

Bus from Santa Maria, RS, BR to Itajaí

Why choose Busbud?

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