Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Midway Truck Plaza Bus Stop | Gateway Station | Cheapest | |||||
| Midway Truck Plaza Bus Stop | Gateway Station | Fastest | |||||
| Midway Truck Plaza Bus Stop | Gateway Station | No tags | |||||
| Columbia Wabash Station | Gateway Station | No tags | |||||
| Columbia Wabash Station | Gateway Station | No tags |
Last refresh of the prices: Today at 2:30 PM CDT.
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Bus Columbia, MO to St. Louis: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Columbia St. Louis recent customer reviews
This Greyhound experience was not great. The bus was late and there was no communication about status while at the partner station. The drivers talked loudly for the duration of the trip which was exhausting to listen to even though I wasn’t sitting anywhere near them.
Naya O.
Bus driver was nasty , vindictive and rude. I may never ride grey hound again because of him.
Rafael R.
1-the bus was cancelled 2- no one contact me even thought my email associated with ticket 3- wouldn't know that bus cancelled if won't spent about 1 hour on phone 4- bad service
Michelle G.
Columbia to St. Louis Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Columbia to St. Louis.
Bus service from Columbia to St. Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Columbia to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Columbia and St. Louis?
Frequently asked questions for your trip Columbia, MO - St. Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbia, MO to St. Louis was searched and found on Oct 11, 2025 with a price of $22To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia, MO to St. Louis, as early as possible.
You can expect to pay from $22 to $107 for a bus ticket from Columbia, MO to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $22 which is on 2025-10-11.
Usually Intercape will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Columbia to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Columbia to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Columbia to St. Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Columbia to St. Louis while indulging in miles on end of beautiful scenic views.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Columbia
Buses Leaving from Columbia
- Bus from Columbia to New York City
- Bus Columbia - Miami
- Columbia - Orlando
- Bus from Columbia to Atlanta
- Bus Columbia - Nashville
- Columbia - Richmond
- Bus from Columbia to St. Louis
- Bus Columbia - Kansas City
- Columbia - Chicago
- Bus from Columbia to Jefferson City
- Bus Columbia - Springfield
- Columbia - Wisconsin Dells
- Bus from Columbia to Champaign
- Bus Columbia - Joplin
- Columbia - Houston
Buses Going to Columbia
- Bus from Chicago to Columbia
- Bus Washington - Columbia
- Nashville - Columbia
- Bus from Charlotte to Columbia
- Bus Athens - Columbia
- Seattle - Columbia
- Bus from St. Louis to Columbia
- Bus Kansas City - Columbia
- Springfield - Columbia
- Bus from Dallas to Columbia
- Bus Houston - Columbia
- Atlanta - Columbia
- Bus from Phoenix to Columbia
- Bus Jefferson City - Columbia
- Lawrence - Columbia
Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Bus St. Louis - Kansas City
- St. Louis - Kansas City
- Bus from St. Louis to Austin
- Bus St. Louis - Nashville
- St. Louis - Buffalo
- Bus from St. Louis to Chicago
- Bus St. Louis - Columbia
- St. Louis - Atlanta
- Bus from St. Louis to Springfield
- Bus St. Louis - Dallas
- St. Louis - Memphis
- Bus from St. Louis to Indianapolis
- Bus St. Louis - Houston
- St. Louis - Orlando
Buses Going to St. Louis
- Bus from New Orleans to St. Louis
- Bus Indianapolis - St. Louis
- Manchester - St. Louis
- Bus from Atlanta to St. Louis
- Bus Manchester - St. Louis
- Omaha - St. Louis
- Bus from Chicago to St. Louis
- Bus Columbia - St. Louis
- Kansas City - St. Louis
- Bus from Springfield to St. Louis
- Bus Carbondale - St. Louis
- Lafayette - St. Louis
- Bus from Dallas to St. Louis
- Bus Nashville - St. Louis
- Houston - St. Louis
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Orlando - Atlanta
- Atlanta - Orlando