Bus Tickets from Durham, NC, US to Winston-Salem

ThuJul 31
FriAug 1
SatAug 2
SunAug 3
from $27
MonAug 4
from $24
TueAug 5
WedAug 6
ThuAug 7

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 3 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham
    Arrival time: August 3 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: August 3 at
    Destination city: Winston-Salem
    Destination location: Winston-Salem, 1425 Silas Creek Pkwy
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham Greyhound Bus Station
    Arrival time: August 3 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 3 at
    Departure city: Durham
    Departure location: Durham
    Arrival time: August 3 at
    Destination city: Winston-Salem
    Destination location: Winston-salem, (NC - Tienda Mexican El Crystal)
    Operated by: ExpresoExpreso
    Vehicle: BusDuration:

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Compare 2 ways to go from Durham to Winston-Salem.

Bus
Average Price$24 - $127Average Duration1h 40m
3kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Train
Average Price$23 - $23Average Duration23h 33m
11kg CO₂e1 out of 5 stars
Cheapest
busbud logoBusbud recommends taking the bus from Durham to Winston-Salem

Among the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 1 hour 40 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.

7bus per day
1h 40mAverage Duration
$24Cheapest ticket
3kgCO₂ emissions

Bus Durham, NC, US to Winston-Salem: Trip Overview

Average ticket price$27
Average bus trip duration1h 40m
Number of daily buses7
Earliest bus departure1:30am
Distance76 miles (121 km)
Latest bus departure4:25pm

Durham to Winston-Salem Bus

Busbud helps you find a bus from Durham to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Winston-Salem.

Discover how much the bus trip from Durham to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Durham, NC, US - Winston-Salem

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/27
$20
07/28
$18
Today
No data
07/30
No data
07/31
No data
08/01
No data
08/02
No data
08/03
$20
busbud logoThe cheapest trip from Durham, NC, US to Winston-Salem was searched and found on Jul 28, 2025 with a price of $18

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Winston-Salem, as early as possible.

You can expect to pay from $18 to $110 for a bus ticket from Durham, NC, US to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-08-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Winston-Salem!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Winston-Salem.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Durham to Winston-Salem will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Durham, NC, US by bus?

Bus from Durham, NC, US to Winston-Salem

You can also go to Winston-Salem by train

Train from Durham, NC, US to Winston-Salem

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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