Bus Tickets from Frankfurt am Main to Prague

Next departures

Next departures for Frankfurt am Main to Prague on October 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
KLR Bus
Frankfurt Main Airport P36
FlorencCheapest
RegioJet
Frankfurt - Main bus station
FlorencFastest
Flixbus
Frankfurt Hbf
PRG AirportNo tags
KLR Bus
Frankfurt Main Train Station
FlorencNo tags
Flixbus
Frankfurt Hbf
PRG AirportNo tags

Last refresh of the prices: Today at 12:04 AM CEST.

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Compare 3 ways to go from Frankfurt am Main to Prague.

Bus
Average Price$19 - $181Average Duration8h 55m
10kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$36 - $281Average Duration7h 28m
10kg CO₂e5 out of 5 stars
Carpool
Average Price$24 - $66Average Duration5h 20m
17kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Frankfurt am Main to Prague

Among the sustainable travel choices, the carpool stands out as the good way to reach Prague. The journey takes about 5 hours 20 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.

3carpool per day
5h 20mAverage Duration
$24Cheapest ticket
17kgCO₂ emissions

Bus Frankfurt am Main to Prague: Trip Overview

Average ticket price$40
Average bus trip duration8h 55m
Number of daily buses29
Earliest bus departure12:20am
Distance256 miles (412 km)
Latest bus departure11:59pm

Frankfurt am Main to Prague Bus

With Busbud, comparing and booking tickets for a bus from Frankfurt am Main to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Frankfurt am Main to Prague will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Frankfurt am Main to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Frankfurt am Main - Prague

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/12
$53
10/13
$41
Today
$27
10/15
$21
10/16
$31
10/17
$20
10/18
$36
10/19
$20
busbud logoThe cheapest trip from Frankfurt am Main to Prague was searched and found on Oct 17, 2025 with a price of $20

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Prague, as early as possible.

You can expect to pay from $20 to $100 for a bus ticket from Frankfurt am Main to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $20 which is on 2025-10-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Frankfurt am Main to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Frankfurt am Main to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Frankfurt am Main to Prague that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Frankfurt am Main to Prague.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Frankfurt am Main by bus?

Bus from Prague to Frankfurt am Main

You can also go to Prague by train

Train from Frankfurt am Main to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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