Bus Tickets from Harrisburg to Buffalo, NY

Next departures

Next departures for Harrisburg to Buffalo on October 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
Buffalo (BUF) AirportCheapest
Greyhound Lines, Inc.
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityFastest
Greyhound Lines, Inc.
Harrisburg Bus Station
Niagara Frontier Transportation AuthorityNo tags

Last refresh of the prices: Yesterday at 2:36 PM EDT.

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Compare 2 ways to go from Harrisburg to Buffalo.

Bus
Average Price$59 - $241Average Duration15h 40m
8kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$160 - $354Average Duration13h 10m
30kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Harrisburg to Buffalo

Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 15 hours 40 minutes and with fares starting at just $59, it presents an excellent value for a comfortable ride.

12bus per day
15h 40mAverage Duration
$59Cheapest ticket
8kgCO₂ emissions

Bus Harrisburg to Buffalo, NY: Trip Overview

Average ticket price$99
Average bus trip duration15h 40m
Number of daily buses12
Earliest bus departure12:20am
Distance208 miles (335 km)
Latest bus departure11:20pm

Harrisburg to Buffalo Bus

Busbud helps you find a bus from Harrisburg to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Harrisburg to Buffalo.

Whether it is cheap bus tickets or more luxurious buses going to Buffalo from Harrisburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Harrisburg - Buffalo, NY

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/13
$109
10/14
No data
Today
$100
10/16
No data
10/17
No data
10/18
No data
10/19
No data
10/20
No data
busbud logoThe cheapest trip from Harrisburg to Buffalo, NY was searched and found on Oct 15, 2025 with a price of $100

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Buffalo, NY, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Harrisburg and Buffalo!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Harrisburg to Buffalo.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Harrisburg to Buffalo.

Make a music playlist for your bus ride from Harrisburg to Buffalo, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Harrisburg to Buffalo, NY?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Buffalo, NY to Harrisburg

You can also go to Buffalo, NY by train

Train from Harrisburg to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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