Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 1052 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the value for money and the ticket access but often complained with the wifi. RegioJet ticket prices on this trip start at $51
Based on 10986 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $345
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Busbud helps you find a bus from Prague to Rome. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Prague to Rome.
Whether it is cheap bus tickets or more luxurious buses going to Rome from Prague, we help you find what you're looking for based on how much of a budget you have.
Via Vincenzo Giudice, 00173 Roma RM, ItalyAnagnina
Frequently asked questions for your trip Prague - Rome
What is the distance between Prague and Rome?
Prague and Rome are 573 miles (925 km) apart.
What are the departure and arrival stations when taking the bus from Prague to Rome?
If you're headed to Rome from Prague, chances are that your bus will depart from Tomíčkova and arrive at Rome Tiburtina Bus Station. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in Rome?
Once in Rome, you can start exploring the city and discover its surroundings. The top sights and things to do are Colosseum, Piazza Navona, Cooking Classes and Food Tours in Rome, Pantheon and Teatro dell'Opera di Roma.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
10/12
$109
10/13
$77
Today
$92
10/15
$88
10/16
$85
10/17
$84
10/18
$86
10/19
$80
The cheapest trip from Prague to Rome was searched and found on Oct 13, 2025 with a price of $77
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Rome, as early as possible.
You can expect to pay from $77 to $259 for a bus ticket from Prague to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-10-19.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Prague and Rome!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Prague to Rome.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Rome.
Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Rome while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
The cheapest trip from Prague to Rome was searched and found on Oct 13, 2025 with a price of $77
