Bus Tickets from San Diego, CA, US to Chicago

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TodayJul 3
from $470
TomorrowJul 4
from $307
SatJul 5
from $305
SunJul 6
from $223
MonJul 7
from $218
TueJul 8
from $196
WedJul 9
from $215
ThuJul 10
from $232

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 4 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: July 6 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 4 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: July 6 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 4 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: July 6 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 4 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: July 7 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 4 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: July 7 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from San Diego to Chicago.

Bus
Average Price$118 - $763Average Duration2d 7h
70kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$175 - $2,079Average Duration2d 19h
254kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 2 days, 7 hours 55 minutes and with fares starting at just $118, it presents an excellent value for a comfortable ride.

22bus per day
2d 7hAverage Duration
$118Cheapest ticket
70kgCO₂ emissions

Bus San Diego to Chicago: Trip Overview

Average ticket price$215
Average bus trip duration2d 7h
Number of daily buses22
Earliest bus departure7:15am
Distance1727 miles (2785 km)
Latest bus departure7:35pm

San Diego to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Chicago.

From cheap bus tickets to more luxurious buses traveling from San Diego to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Diego, CA, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/01
$390
07/02
$470
Today
$523
07/04
$433
07/05
$318
07/06
$289
07/07
$300
07/08
$259
busbud logoThe cheapest trip from San Diego to Chicago was searched and found on Jul 8, 2025 with a price of $259

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Chicago, as early as possible.

You can expect to pay from $259 to $582 for a bus ticket from San Diego to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $259 which is on 2025-07-08.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from San Diego to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to Chicago

You can also go to Chicago by train

Train from San Diego to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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