Bus Tickets from San Francisco, US to Calexico

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TodayJul 4
TomorrowJul 5
SunJul 6
from $97
MonJul 7
TueJul 8
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FriJul 11

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 6 at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: July 7 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 6 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 7 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 6 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 7 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 6 at
    Departure city: San Francisco
    Departure location: 409 Townsend St, SF
    Arrival time: July 7 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 6 at
    Departure city: San Francisco
    Departure location: San Francisco Bus Station
    Arrival time: July 7 at
    Destination city: Calexico
    Destination location: Calexico Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Francisco to Calexico: Trip Overview

Average ticket price$115
Average bus trip duration18h 30m
Number of daily buses3
Earliest bus departure11:35am
Distance524 miles (845 km)
Latest bus departure11:25pm

San Francisco to Calexico Bus

Busbud helps you find a bus from San Francisco to Calexico. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Francisco to Calexico will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from San Francisco to Calexico, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Francisco, US - Calexico

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/02
$107
07/03
No data
Today
No data
07/05
No data
07/06
$90
07/07
No data
07/08
No data
07/09
No data
busbud logoThe cheapest trip from San Francisco to Calexico was searched and found on Jul 6, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco to Calexico, as early as possible.

You can expect to pay from $90 to $107 for a bus ticket from San Francisco to Calexico based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-07-06.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Francisco and Calexico!

Much more than a mere vehicle taking you from San Francisco to Calexico, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to Calexico that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Francisco to Calexico while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Francisco by bus?

Bus from San Francisco to Calexico

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