Bus Tickets from Santiago, CL to San Luis, AR

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TodayJul 14
TomorrowJul 15
from $59
WedJul 16
ThuJul 17
FriJul 18
SatJul 19
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MonJul 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: July 15 at
    Departure city: Santiago
    Departure location: Santiago De Chile
    Arrival time: July 15 at
    Destination city: San Luis
    Destination location: Ediro San Luis
    Operated by: Tu EnvidiaTu Envidia
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: July 15 at
    Departure city: Santiago
    Departure location: Santiago De Chile
    Arrival time: July 15 at
    Destination city: San Luis
    Destination location: Ediro San Luis
    Operated by: Tu EnvidiaTu Envidia
    Vehicle: BusDuration:
  • Departure time: July 15 at
    Departure city: Santiago
    Departure location: Santiago De Chile
    Arrival time: July 15 at
    Destination city: San Luis
    Destination location: Ediro San Luis
    Operated by: Tu EnvidiaTu Envidia
    Vehicle: BusDuration:

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Bus Santiago to San Luis: Trip Overview

Average ticket price$86
Average bus trip duration9h
Number of daily buses1
Earliest bus departure7:30am
Distance253 miles (407 km)
Latest bus departure12:00pm

Santiago to San Luis Bus

With Busbud, comparing and booking tickets for a bus from Santiago to San Luis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Santiago to San Luis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Santiago to San Luis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Santiago, CL - San Luis, AR

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/12
No data
07/13
No data
Today
No data
07/15
$55
07/16
No data
07/17
No data
07/18
$57
07/19
No data
busbud logoThe cheapest trip from Santiago to San Luis was searched and found on Jul 15, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to San Luis, as early as possible.

You can expect to pay from $55 to $68 for a bus ticket from Santiago to San Luis based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-07-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Santiago to San Luis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santiago to San Luis, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santiago to San Luis will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago to San Luis while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Santiago by bus?

Bus from Santiago to San Luis

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