Bus Tickets from Tupelo to Charlotte, NC

Next departures

Next departures for Tupelo to Charlotte on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte (Freedom Dr)Cheapest
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Tupelo (Brothers Quick Stop)
Charlotte Bus StationNo tags

Last refresh of the prices: Last Friday at 11:28 AM CDT.

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Bus Tupelo to Charlotte, NC: Trip Overview

Average ticket price$73
Average bus trip duration11h 55m
Number of daily buses3
Earliest bus departure10:55am
Distance450 miles (725 km)
Latest bus departure11:15pm

Tupelo to Charlotte Bus

With Busbud, comparing and booking tickets for a bus from Tupelo to Charlotte is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Tupelo to Charlotte will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Charlotte from Tupelo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Tupelo - Charlotte, NC

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/10
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10/11
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Today
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10/13
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10/14
$75
10/15
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10/16
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10/17
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busbud logoThe cheapest trip from Tupelo to Charlotte, NC was searched and found on Oct 14, 2025 with a price of $75

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Charlotte, NC, as early as possible.

You can expect to pay from $75 to $75 for a bus ticket from Tupelo to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Tupelo to Charlotte.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Tupelo to Charlotte, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tupelo to Charlotte.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tupelo to Charlotte.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Tupelo by bus?

Bus from Charlotte, NC to Tupelo

Why choose Busbud?

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