Bus Tickets from Wytheville to Philadelphia, PA

Next departures

Next departures for Wytheville to Philadelphia on October 19
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Wytheville Bus Station
Philadelphia, 199 Spring Garden StCheapest
Greyhound Lines, Inc.
Wytheville Bus Station
199 Spring Garden St.Fastest
Greyhound Lines, Inc.
Wytheville Bus Station
199 Spring Garden St.No tags
Greyhound Lines, Inc. + FlixBus
Wytheville Bus Station
Philadelphia, 199 Spring Garden StNo tags
Greyhound Lines, Inc. + FlixBus
Wytheville Bus Station
Cherry Hill MallNo tags

Last refresh of the prices: Today at 9:17 AM EDT.

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Bus Wytheville to Philadelphia, PA: Trip Overview

Average ticket price$142
Average bus trip duration17h 50m
Number of daily buses7
Earliest bus departure2:45am
Distance358 miles (577 km)
Latest bus departure8:55am

Wytheville to Philadelphia Bus

Busbud helps you find a bus from Wytheville to Philadelphia. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Wytheville to Philadelphia from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Philadelphia from Wytheville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Wytheville - Philadelphia, PA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/16
No data
10/17
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Today
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10/19
$147
10/20
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10/21
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10/22
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10/23
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busbud logoThe cheapest trip from Wytheville to Philadelphia, PA was searched and found on Oct 19, 2025 with a price of $147

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wytheville to Philadelphia, PA, as early as possible.

You can expect to pay from $147 to $159 for a bus ticket from Wytheville to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2025-10-19.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wytheville and Philadelphia!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Wytheville to Philadelphia, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wytheville to Philadelphia.

Make a music playlist for your bus ride from Wytheville to Philadelphia, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Wytheville by bus?

Bus from Philadelphia, PA to Wytheville

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