Trains tickets from St. Louis to San Diego, CA, US

Frequently asked questions for your trip St. Louis - San Diego, CA, US

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/12
$267
10/13
$547
Today
$229
10/15
No data
10/16
No data
10/17
No data
10/18
No data
10/19
No data
busbud logoThe cheapest trip from St. Louis to San Diego, CA, US was searched and found on Oct 14, 2025 with a price of $229

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St. Louis to San Diego, CA, US, as early as possible.

About Train Travel

Train Travel Tips

Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between St. Louis and San Diego is also a great way to travel to arrive in the city centre and save more time for your stay in San Diego.

Regional train? High-speed train? Whichever train to San Diego you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

By choosing the train between St. Louis and San Diego, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from St. Louis to San Diego.

Did you know?

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.

The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.

Will you be returning to St. Louis by train?

Train from San Diego, CA, US to St. Louis

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Popular Trains Connecting St. Louis

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