Bus Tickets from Buffalo, NY to St. Louis

Previously seen trips

Next departures for Buffalo to St. Louis on October 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Buffalo (BUF) Airport
Gateway StationNo tags
Greyhound
Niagara Frontier Transportation Authority
Gateway StationNo tags
Greyhound + FlixBus
Buffalo (BUF) Airport
Gateway StationNo tags
FlixBus + Greyhound
Niagara Frontier Transportation Authority
Gateway StationNo tags
Greyhound + FlixBus
Buffalo (BUF) Airport
Gateway StationNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Buffalo to St. Louis

Bus
Average PriceUS$91 - US$282Average Duration1d 10h
27kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$123 - US$294Average Duration19h 28m
98kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Buffalo to St. Louis

Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 19 hours 28 minutes, and with fares starting at just US$123, it presents an excellent value for a comfortable ride.

2train per day
19h 28mAverage Duration
US$123Cheapest ticket
98kgCO₂ emissions

Bus Buffalo, NY to St. Louis: Trip Overview

Average Ticket PriceUS$140
Average Bus Trip Duration1d 10h
Number of daily buses6
Earliest bus departure7:55am
Distance1077 km
Latest bus departure11:59pm

Buffalo to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Buffalo to St. Louis.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to St. Louis.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Buffalo, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Buffalo, NY - St. Louis

  1. How much does a bus ticket from Buffalo to St. Louis cost?

    The bus ticket price from Buffalo to St. Louis starts at US$91. The best way to find cheap bus tickets from Buffalo to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Buffalo to St. Louis?

    The average travel time between Buffalo and St. Louis is around 1d 10h, although the fastest bus will take about 23h 30m.This is the time it takes to travel the 1065 km that separates the two cities.

  3. How many daily bus connections are there between Buffalo and St. Louis?

    The number of buses from Buffalo to St. Louis can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Buffalo to St. Louis by comparing and selecting the bus that fits you travel style and budget on Busbud.

  4. Which bus companies travel from Buffalo to St. Louis?

    When taking the bus from Buffalo to St. Louis, you can travel comfortably and safely with Greyhound, FlixBus.

  5. What are the departure and arrival stations when taking the bus from Buffalo to St. Louis?

    Buses travelling between Buffalo and St. Louis leave from Buffalo Airport or Transportation Center and arrive at Gateway Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-15
US$136
10-16
US$130
Today
No data
10-18
No data
10-19
No data
10-20
No data
10-21
US$86
10-22
US$83
busbud logoThe cheapest trip from Buffalo, NY to St. Louis was searched and found on Oct 22, 2025 with a price of US$83

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to St. Louis, as early as possible.

You can expect to pay from US$83 to US$195 for a bus ticket from Buffalo, NY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$83 which is on 2025-10-22.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Buffalo to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Buffalo to St. Louis.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Buffalo to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Buffalo to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Buffalo, NY to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo, NY by bus?

Bus from St. Louis to Buffalo, NY

You can also go to St. Louis by train

Train from Buffalo, NY to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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