Bus Tickets from Prague to Mainz

Previously seen trips

Next departures for Prague to Mainz on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Prague (Central Bus Station Florenc)
MainzNo tags
FlixBus
Prague (Main Railway Station)
MainzNo tags
FlixBus
Prague (Central Bus Station Florenc)
MainzNo tags
FlixBus
Prague (Na Knížecí)
MainzNo tags
FlixBus
Prague (Central Bus Station Florenc)
MainzNo tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Prague to Mainz

Bus
Average PriceUS$36 - US$121Average Duration10h 50m
11kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$43 - US$178Average Duration8h 47m
11kg CO₂e5 out of 5 stars
Carpool
Average PriceUS$26 - US$39Average Duration5h 30m
19kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Prague to Mainz

Among the sustainable travel choices, the carpool stands out as a good way to reach Mainz. The journey takes about 5 hours 30 minutes, and with fares starting at just US$26, it presents an excellent value for a comfortable ride.

5carpool per day
5h 30mAverage Duration
US$26Cheapest ticket
19kgCO₂ emissions

Bus Prague to Mainz: Trip Overview

Average Ticket PriceUS$48
Average Bus Trip Duration10h 50m
Number of daily buses6
Earliest bus departure3:50am
Distance429 km
Latest bus departure10:45pm

Prague to Mainz Bus

With Busbud, comparing and booking tickets for a bus from Prague to Mainz is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Prague to Mainz will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Mainz from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Prague - Mainz

  1. What is the travel distance from Prague to Mainz?

    The distance covered from Prague to Mainz is 440 km (273 miles).

  2. What are the departure and arrival locations for buses traveling from Prague to Mainz?

    Buses traveling this route start their trip at PRG Airport, in Prague, and end it at Mainz, in Mainz.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-11
US$46
10-12
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busbud logoThe cheapest trip from Prague to Mainz was searched and found on Oct 11, 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Mainz, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Prague to Mainz.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Prague to Mainz, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Mainz.

Tune out to the fine sounds of your best music playlist on your bus trip from Prague to Mainz while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Prague by bus?

Bus from Mainz to Prague

You can also go to Mainz by train

Train from Prague to Mainz

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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