Find coaches from St. Louis to San Diego, CA, US

Previously seen journeys

Next departures from St. Louis to San Diego on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
St Louis, MO
Downtown SD (Seaport)No tags
Greyhound + FlixBus
Gateway Station
UCSD Health La Jolla StationNo tags
FlixBus + Greyhound
Gateway Station
San Diego (Old Town-FlixBus)No tags
Greyhound + FlixBus
Gateway Station
Downtown SD (Seaport)No tags
Greyhound
Gateway Station
Greyhound Bus StopNo tags

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus St. Louis to San Diego, CA, US: Trip Overview

Average ticket priceUS$187
Average bus trip duration2d 1h
Number of daily buses13
Earliest bus departure01:20
Distance1551 miles
Latest bus departure23:30

St. Louis to San Diego Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St. Louis to San Diego.

We make sure you can find a bus service from St. Louis to San Diego from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from St. Louis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip St. Louis - San Diego, CA, US

  1. How far is San Diego from St. Louis by coach?

    The journey from St. Louis to San Diego by coach covers an approximate distance of 1560 miles (2516 km).

  2. Is there a way to reach San Diego from St. Louis without flying?

    To travel from St. Louis to San Diego without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
US$129
12/10
US$322
Today
No data
14/10
US$157
15/10
No data
16/10
No data
17/10
No data
18/10
No data
busbud logoThe cheapest trip from St. Louis to San Diego, CA, US was searched and found on 11 Oct 2025 with a price of US$129

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to San Diego, CA, US as early as possible.

You can expect to pay from US$129 to US$322 for a bus ticket from St. Louis to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$157, which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St. Louis to San Diego but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St. Louis to San Diego, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from St. Louis to San Diego.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to San Diego.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to St. Louis by bus?

Bus from San Diego, CA, US to St. Louis

You can also go to San Diego, CA, US by train

Train from St. Louis to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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