Bus Tickets from Chicago to Durham, NC, US

Next departures

Next departures for Chicago to Durham on October 11
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Chicago 95Th & Dan Ryan
Durham Greyhound Bus StationCheapest
FlixBus
Chicago 95Th & Dan Ryan
Durham Greyhound Bus StationFastest
Greyhound Lines, Inc.
Downtown Greyhound Station
Durham Greyhound Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Downtown Greyhound Station
Durham Greyhound Bus StationNo tags
FlixBus
Downtown Greyhound Station
Durham Greyhound Bus StationNo tags

Last refresh of the prices: Yesterday at 4:10 PM CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Chicago to Durham.

Bus
Average Price$82 - $309Average Duration1d 1h
25kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$280 - $280Average Duration1d 13h
91kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Chicago to Durham

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 1 day, 1 hour 45 minutes and with fares starting at just $82, it presents an excellent value for a comfortable ride.

11bus per day
1d 1hAverage Duration
$82Cheapest ticket
25kgCO₂ emissions

Bus Chicago to Durham, NC, US: Trip Overview

Average ticket price$176
Average bus trip duration1d 1h
Number of daily buses11
Earliest bus departure12:30am
Distance612 miles (987 km)
Latest bus departure11:59pm

Chicago to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Chicago to Durham.

Bus service from Chicago to Durham will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Durham from Chicago, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Chicago - Durham, NC, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/08
$130
10/09
$130
Today
$158
10/11
$139
10/12
No data
10/13
$120
10/14
No data
10/15
No data
busbud logoThe cheapest trip from Chicago to Durham, NC, US was searched and found on Oct 13, 2025 with a price of $120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Durham, NC, US, as early as possible.

You can expect to pay from $120 to $265 for a bus ticket from Chicago to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-10-13.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Chicago to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Chicago to Durham, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Chicago to Durham.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Chicago to Durham, NC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Chicago by bus?

Bus from Durham, NC, US to Chicago

You can also go to Durham, NC, US by train

Train from Chicago to Durham, NC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular Buses Connecting Durham

Buses Leaving from Durham

Buses Going to Durham